Spectroscopy

Spectroscopy, is the study of absorption and emission of electromagnetic waves by matter. The definition includes the study of the interactions between particles such as electrons, protons, and ions. Spectroscopic analysis has been crucial in the development of pharmaceuticals for examining drug identity and purity, drug crystalline structures, interactions between active ingredients and excipients, patent of antibiotics, and much more.

Pharmaceutical spectroscopy equipment comes in many forms, and its variety makes it accessible to a broad range of research professionals working within diverse budgets.

Spectroscopy Equipment Includes

• Gas and Liquid Chromatography Mass Spectrometers
• FTIR/ IR Spectroscopy Machines
• Raman Microscopes and Spectrometers
• Time of Flight Spectrometers
• X-Ray Spectrometers

Gas chromatography/mass spectroscopy (GC/MS) is utilized in the analysis of organic compounds. Gas chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. GC-MS has considered a high-level benchmark for substance identification because it is used to perform a 100% specific test, positively identifying a particular substance.

Liquid chromatography/mass spectroscopy(LC/MS) is a versatile analytical method commonly employed during all phases of pharmaceutical drug development because of its regarded speed, sensitivity, and selectivity. It is commonly used during final analyses of the drug approval process. LC/MS identifies proteins, detects metabolites, determines the molecular weight of drugs, verifies molecular structures and detects for impurities and degradants.

Infrared spectroscopy is a versatile method for the determination of pharmaceutical compounds and functional groups within molecules. It measures energy absorption across the infrared frequency range. Gas, liquid, or solid pharmaceutical samples can be analyzed by infrared spectroscopy. The Fourier transform infrared (FTIR) spectroscopic method, by which an interferometer is used in place of a monochromator, allows for simultaneous analysis across the infrared frequency range. Due in part to its speed and sensitivity, FTIR has become the standard of pharmaceutical infrared spectroscopy analysis.