Software Drives Property-Based Optimization of Pharmaceutical Lead Compounds

[Article Title]

Synthetic medicinal chemists strive to produce compounds in accordance with ADME-Tox and physicochemical property requirements. However, doing this while simultaneously striving for maximum potency is a challenging and labor-intensive task. Creating hundreds or thousands of analogs in order to identify the optimal drug candidate involves not only synthetic chemistry, but also various specialist groups that support synthetic efforts with compound testing and evaluation.

Software can help medicinal chemists test structure modification ideas prior to the synthesis of new analogs, prioritize synthetic modifications based on full and reliable physicochemical and ADME-Tox profiles, and ensure that project teams do not miss the most promising candidate.

Learn more in this application note from Revvity Signals!

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