Formulation Development β-GalNAc-PEG4-Azide from Alfa Chemistry - Product Description and Details

Description

Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry

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β-GalNAc-PEG4-Azide

Product Specs
Itemβ-GalNAc-PEG4-Azide
CompanyAlfa Chemistry
PriceGet quote
Catalog NumberACM879004929
Quantity100
Applicationβ-GalNAc-PEG4-Azide is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; incorporates a single ASGPR ligand with a PEG4 linker and azide group reactive handle ready for conjugation. It can be used as a building block for multivalent compounds to enhance ASGPR binding. Upon binding to ASGPR, β-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. β-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA in a cell-specific manner to hepatocytes. Can be used to generate LYTACs, or labeled with dye for tissue imaging.
Purity / Grade>95% (HPLC)

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