SMART SOLUTIONS START HERE. BECAUSE HEALTH MATTERS.
At DuPont, we aim to help our pharma customers with both everyday challenges and future solutions. Armed with essential excipients and vital expertise, our portfolio is designed to deliver performance and cost advantages in various oral solid dosage forms. Couple that with leading QbD programs, regulatory expertise and a network of global technical experts, we can help deliver a consistent, high-quality offering, at the right time, every time.
DuPont draws from the rich experience of historically market-leading excipient companies who pioneered brands like Avicel®, the first pharma tablet binder, METHOCEL™, a leading brand across multiple applications, Ac-Di-Sol®, a superdisintegrant, and POLYOX®, an enabling polymer with varied functionality. Four Pharma-dedicated global research facilities and a wide manufacturing network locate us close to customers.
DuPont provides solutions for tablets, capsules, multi-particulates and suspensions in immediate, delayed, and sustained release; enhanced bioavailability; and robust encapsulation.
Whether you’re creating modified release formulations, looking for efficient binding, coating or taste masking, seeking to enhance the solubility of APIs or to launch vegetarian soft/hard capsules for a growing population, DuPont can help.
BROAD EXCIPIENT PORTFOLIO
Immediate Release
- More than 50 years developing solutions for various formulations and manufacturing platforms
- Avicel® PH and co-processed grades for wet granulation and to improve compactability for direct and roller compaction
- METHOCEL™ for wet granulation and tablet ‑ lm coating applications
- Ac-Di-Sol® for rapid tablet disintegration
- Alubra® lubricant for poorly water-soluble APIs and less sensitive to over lubrication
Controlled Release
- We control the release of APIs across applications and provide versatility in drug release rates.
- METHOCEL™ for matrix-controlled release applications
- ETHOCEL™ barrier membrane coating for multi-particulates and tablets
- Aquacoat® aqueous-based, ethyl cellulose CR coating for multiparticulatesand tablets
- POLYOX™ rapidly swelling material for osmotic pump and crush resistant matrix tablets
Taste-Masking, Solubility Enhancement, Encapsulation
- ETHOCEL™ and Aquacoat® ECD provides taste masking without compromising dissolution
- AFFINISOL™ inhibits crystallization of the API, improving solubility in solid dispersions
- SEAGEL® soft capsule technology and METHOCEL™ hard shell capsules enable vegetarian claims
REGULATORY DEPTH
Our global product stewardship and regulatory specialists have a demonstrated track record of collaborating to help customers more seamlessly navigate this dynamic area.
VITAL EXPERTISE
Our QbD initiatives support formulation and scale-up activities. Five of DuPont’s manufacturing facilities have EXCiPACT GMP Certification Standards, with the remainder on track by the end of 2020.
PROBLEM SOLVING AND KNOWLEDGE SHARING
Knowledge sharing drives innovation and generates answers to pressing challenges. We work with customers via Health by Design programs to optimize formulations and brainstorm future possibilities.