Description
To facilitate the smooth transition of candidate antibodies from animal models to human clinical research, CD ComputaBio offers an advanced Antibody Humanization Service. Our computational platform identifies non-human framework regions within animal-derived antibodies and meticulously grafts the complementarity-determining regions (CDRs) onto suitable human germline frameworks. Backed by fine-tuned structural modeling, we carefully maintain parental binding affinity and specificity while significantly reducing potential immunogenicity in patients.