Accelerating Advancement in Gene Therapy by Improving Downstream Purification of Viral Vectors

Adeno-Associated Virus (AAV) has become the vector of choice in many gene therapies. Recent advances in chromatography resin development for viral vectors have demonstrated that AAV purification can be scalable and efficient, achieving high purity and yield in a single step. With an extensively growing pipeline of gene therapy clinical trials it is evident that scalable production solutions are needed. Here we outline the benefits of implementing affinity chromatography in the downstream purification of viral vectors.

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