Pharmaceutical and biopharmaceutical manufacturers need faster data related to microbial contamination in all aspects of production. Relying on growth-based methods that take days is not fast enough to make actionable changes when drugs and potentially patient lives are at risk. The implementation of Rapid Microbiological Methods (RMMs) that correlate to traditional plate counts, such as the new Sievers rapid bioburden analyzer, can provide timely trend analysis and early warnings of contamination events in various stages of the manufacturing process.