The Role of Lipids in Mitigation of Food Effect

[Article Title]

Food can either increase or decrease the oral bioavailability of drugs, potentially leading to a change in their pharmacological effect. Therefore, assessing the food effect on the bioavailability of a drug is important to optimize its efficacy and safety. Since the change in bioavailability can depend on the amount of lipid in the food, the clinical studies for food effect include low and high-fat meals as described by FDA Guidelines.
In this paper, learn how the role of lipids has been explained along with their digestion and absorption mechanisms.

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