![[Article Title]](https://media.americanpharmaceuticalreview.com/m/28/article/621162-134x100.jpg)
Explore the effectiveness of a 3D spheroid model with live-cell analysis for compound screening. By evaluating a compound library, assessment of spheroid size and viability is obtained, with phenotypic screening quantifying growth and cytotoxicity, offering a comprehensive alternative to traditional methods. The 3D model shows promise for improved in vitro to in vivo translation, enhancing drug discovery and supporting multifaceted investigations for effective treatments.