The use of lipids in sustained release formulations is growing. Lipid excipients delivery the drug by creating an insoluble matrix structure from which diffusion is the principal drug release mechanism. It not only forms a water-insoluble matrix, but provides pH-independent release, non-digestible, highly resistant to physiological conditions, and does not result in alcohol-related dose dumping. Lipid-based drug delivery (LBDD) systems are well suited for poorly water-soluble, lipophilic, hydrophobic APIs. Lipid-based formulations are categorized into four types on the basis of composition, dispersion, and digestion characteristics.