Since layer-by-layer (LbL) polyelectrolyte assembly was introduced in the nineteen nineties, it has found application in various fields that study and apply nanotechnology. LbL nanoassembly is based on the sequential adsorption of positively and negatively charged polymers on a surface to form a nano-thick film of coating. The process involves resaturation of polyion adsorption, resulting in the reversal of the terminal surface charge of the film after deposition of each layer. The method provides the possibility of designing ultrathin multilayer films with a precision better than one nanometer of defined molecular composition. These films can be applied to surfaces or can be used to coat micro- and nanoparticles. This coating process can be used to control the release of drugs, increase the stability of drugs and to improve the properties of commonly used excipients. Since no covalent binding is involved in the shell formation it allows the drug or excipient to remain intact. Therefor
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