Drug Delivery

Drug delivery is the method in which a pharmaceutical compound is administered to promote a therapeutic effect. Drug delivery routes can include oral, transdermal, nasal, and sublingual application and can directly impact a drugs efficacy. In this drug delivery content hub, you can discover editorial coverage of the latest research and industry trends impacting drug delivery and novel drug discovery.

Unlocking Bioavailability: Advances in Solubility Enhancement Strategies for Oral and Parenteral Drug Administration
Poor aqueous solubility remains one of the most difficult challenges in pharmaceutical development, affecting up to 90% of new chemical entities (NCEs) and over 40% of those in reformulation. Low solubility impairs dissolution, absorption, and pharmacokinetics, resulting in poor bioavailability, increased formulation complexity, and a higher risk ... read more
Empowering Patients at Home: How Micro Vial Innovations in Drug Packaging Enhance Treatment Adherence
The healthcare sector is undergoing a profound transformation as at-home injectable treatments become increasingly prevalent. read more
Advancements in Modified Release Drug Delivery Systems: Technologies, Applications, and Patient-Centric Perspectives
Oral drug delivery remains the most preferred route of administration due to its convenience, cost-effectiveness, and high patient compliance. However, conventional immediate-release (IR) formulations often result in fluctuations in plasma drug concentrations, necessitating frequent dosing and potentially causing side effects due to peak to-trough ... read more

cGMP Radiosynthesis for Early Phase Clinical Trials: A Unique Challenge and Development of a Standard Process
Radiolabeled drugs are used in human ADME and bioavailability studies. read more
Detailed Formulation Development Helps Avoid Production Problems
Developing a robust tablet formulation that can be scaled into product manufacturing can be a difficult challenge. read more
Preventing Sticking and Picking Through Tablet Design
Sticking and picking are two common problems encountered in tablet manufacturing. read more
Tool Life Expectancy
Tooling is a significant investment for companies. read more
Contamination Control: Cleaning and Disinfecting Techniques for Controlled Environments
Effective contamination control procedures require high-quality cleaning equipment and specialized techniques. Critical cleaning professionals recommend the use of multi-bucket mopping systems for maximum cleanliness, efficiency and removal of contaminants. read more

Optimizing Lipid Nanoparticles (LNPs) Processing for siRNA Delivery by Microfluidics System
Optimizing lipid nanoparticles (LNPs) processing for siRNA delivery by microfluidics system read more

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