Formulation Development

Pharmaceutical formulation development is the critical step which links the discovery of a novel drug to commercialization. During this step, formulation scientists will determine the best drug delivery vehicle and dosage form needed to deliver a therapeutic effect based on bioavailability or other factors. Below you can explore articles, industry trends, and curated products which can help increase formulation development efficiency.

An Interview with Sabrina Graf- COO, Tenthpin
I think the main developments have been the automation of complex processes, the improvement of data accuracy, and ensuring adherence to regulatory standards (GxP). This is what we hear from the top and leading global pharma companies as well when working with them. Vast datasets can be monitored in real-time, promptly identifying deviations or ... read more
An Interview with Scott Bone – Head of Formulation and Process Science, Bend Bioscience
The industry must adopt a science-driven, data-informed development strategy. A foundational understanding of the active pharmaceutical ingredient’s (API) physicochemical properties, the matrix characteristics, and the drug’s pharmacokinetic (PK) and pharmacodynamic (PD) profiles is essential. Leveraging these insights early in development ... read more
Pharmaceutical P.I.N. Points: Patent Innovation News
The purpose of this column is to highlight and summarize recent key patents in the pharmaceutical arena issued by the US Patent Office in March 2025. read more

ebook: Lipid Excipients to Unlock Oral Bioavailability Issues
Oral dosage forms favor good patient acceptance and compliance in great part because they are easy to take. However, achieving sufficient bioavailability by the oral route can be challenging due to the complexity of the gastrointestinal (GI) tract. read more
Extractables and Leachables Research is Gaining Maturity
The pharmaceutical and medtech industries, along with their associated regulators, are paying increasing attention to testing requirements for extractables and leachables (E&L) to guarantee the safety, quality and efficacy of their products. read more
Manufacturing of Highly Potent APIs with Best-Practice Safety and Containment Control Procedures
It is a key regulatory and safety requirement that prospective hazards associated during the handling of HPAPIs are identified and understood to enable the development of Occupational Exposure Limits (OEL). read more
The NEXT GENERATION in Protein Characterization
The ability to measure and characterize changes in the secondary structure of proteins is critical to many research applications, especially the formulation and development of biotherapeutics. read more
Benefits of Using High-Functionality Excipients in a Continuous Manufacturing Process
As pharmaceutical companies move increasingly toward changing production methods from batch to continuous processing, there is a need to re-evaluate the types and formulations of the excipients used. read more