Articles in this Issue
The title of this review article is somewhat incorrect, as a bacterium has no intent outside survival and passing on its genes to future generations. In contrast, decisions by manufacturers, ...
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The global biopharmaceutical market is estimated to grow to $3.9B by 2024 - a CAGR of 8.59%, with the majority of the growth in monoclonal antibodies. This growth will be through larger numbers and ...
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Vibrational Spectroscopy in terms of Raman and infrared spectroscopy is a powerful toolbox for the analysis of solutions containing Active Pharmaceutical Ingredients (API). In this article, we provide...
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SARS-CoV-2, the virus responsible for the global COVID-19 pandemic, has caused millions of infections and more than five million deaths worldwide to date. Although the speed with which COVID-19 ...
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A primary tenant of aseptic manufacturing is controlling the environment microbiologically before, during, and after a manufacturing batch. The static and operational controls include the combined ...
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The events of the past two years have made a profound impact on biopharmaceutical companies and every cog in the wheel of our industry. Internally, firms were forced to make radical shifts in ...
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Antibody-Drug Conjugates (ADCs) are an evolving therapeutic modality with an unprecedented ability to target and destroy cancer cells. They were developed to improve upon conventional chemotherapies’ ...
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Excessive headspace foaming within mammalian bioreactor systems can become highly problematic for upstream bioprocesses. Consequences of foam accumulation can result in decreased cell culture growth, ...
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Now more than ever companies manufacturing parenteral products with aseptic filling are urged to look at barrier technologies, either Restricted Access Barrier Systems (RABS) or isolators. This ...
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Recombinant Adeno-Associated Virus (rAAV) is the leading vehicle for delivery of gene products for the treatment of gene therapy. Low production yields and product quality contribute to high ...
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Rapid Microbial Methods are a great example of this development. Rapid technologies, such as Celsis® instruments, allow laboratories to detect microbial contamination in half the time compared to ...
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Implementing Real-Time Testing (RTT) or Real-Time Release Testing (RTRT) in pharmaceutical manufacturing is becoming a more widespread goal to improve efficiency when it comes to assuring quality ...
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What’s that ‘secret’ ingredient that makes up our protein-filled foods, powders, and bars we consume nearly every day after the gym? If you guessed amino acids, you’re spot on! Yes, amino acids are ...
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The purpose of this column is to highlight and summarize recent key patents in the pharmaceutical arena issued by the US Patent Office in May-June 2022.
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