The processability of pharmaceutical powders plays a key role in the design and improvement of tableting processes. It is, therefore, important to characterize the material properties and the behavior of bulk powder to optimize processing methods. Good flowing and densification properties are required for filling of the dies of the tableting system and compaction of the powder. The rheological properties of pharmaceutical powders have been investigated with the rotating drum method (GranuDrum) and tapped density method (GranuPack) and correlated with the performance achieved in a tableting system. The ability of powders to build up charge during flow is also investigated with the GranuCharge and correlated with the flowability and the processability of the powders.
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