Solubilizer Excipients

Poorly soluble drugs are a major issue for the pharmaceutical industry. By using solubility enhancement excipients pharmaceutical formulators can increase the bioavailability of the active pharmaceutical ingredient (API). Advanced solubility enhancement excipients can help companies bring products to market faster. Developing pharmaceutical formulations with appropriate solubility will continue to be one of the key challenges of next years.

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Featured products
Captex 350 Glycerol Tricaprylate/Caprate/Laurate ABITEC	Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Acconon Mixtures for Bioavailability and Emulsion ABITEC	Solubilizer, Emulsifier, Solvent	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Capmul MCG and Propylyene Glycol Esters ABITEC	Solubilizer, Emulsifier, Solvent	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Caprol Polyglycerol Esters ABITEC	Solubilizer, Emulsifier	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Captex 200P ABITEC	Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Captex 810D Glycerol Tricaprylate/Caprate/Linoleate ABITEC	Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Captex Medium Chain Esters ABITEC	Solubilizer, Emulsifier, Solvent	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Biorise Bioavailability Enhancement Technology Adare Pharmaceuticals	Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Kollidon VA 64 BASF North America Related Related Featured Article	Binder	Dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Widely used in HME processes.	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Kolliphor EL BASF North America Related Related Featured Article	Solubilizer	Nonionic emulsifier for O-W emulsions, Solubilizer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Kolliphor ELP BASF North America	Solubilizer	For sensitive active ingredients to improve their stability	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Kolliphor RH40 BASF North America Related Related Featured Article	Solubilizer	Solubiliser, Plasticizer for coating & polymeric matrices, Nonionic emulsifier for O-W emulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Kollisolv P 124 BASF North America	Solubilizer	Liquid plasticizer for tablet coatings, Solvent for APIs, dispersing agent, stabilizer and co-emulsifier in semi-solid formulations	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Soluplus BASF North America Related Related Featured Article Related Featured Product APR	Binder	Increase solubility and bioavailability, Ideal for hot melt extrusion (HME)	Get quote White Paper SDI Phase	Compare or Get quote for selected.
galenIQ™ 990 for High-Boiled Lozenges BENEO-Palatinit GmbH	Bulk, Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
galenIQ™ 720 for Direct Compression BENEO-Palatinit GmbH	Sweetener, Filler, Binder, Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
galenIQ™ 721 for Direct Compression BENEO-Palatinit GmbH	Sweetener, Filler, Binder, Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Captisol® Captisol®, A Ligand Technology	Solubilizer, Increased bioavailability, Stabilizer	Improves solubility, stability, bioavailability and dosing of APIs	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Crodasol™ HS HP Croda Related Related Featured Product APR	Solubilizer, Emulsion Stabilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Super Refined™ Castor Oil Croda	Emulsifier, Solubilizer, Solvent	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Super Refined™ PEG 400 Croda	Viscosity Modifier, Solvent, Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Super Refined™ Polysorbate 80 Croda	Emulsifier, Plasticiser, Solubiliser	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Super Refined™ Propylene Glycol Croda	Solubilizer, Emulsifier	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Synperonic™ PE Poloxamers Croda	Solubilizer, Emulsifier, Surfactant	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Capryol PGMC Gattefossé	Inquire	Solubilizer, Bioavailability enhancer, Water insoluble surfactant for SELF, Solubilizer for actives, W/O surfactant	Get quote White Paper SDI Phase	Compare or Get quote for selected.
CapryolTM 90 Gattefossé	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, Inhalation products, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, Inhalation products, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 44/14 Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 48/16 Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 50/13 Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into coarse emulsion—LFCS Type III (SMEDDS). Modulation of drug release. Lipid binder in melt processes.	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Matrix for modified release, Multiparticulates	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafac™ PG Gattefossé	Oily phase for topical formulations. Oily vehicle and solubilizer for solutions.	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafac™ lipophile WL 1349 Gattefossé	Oily vehicle in LFCS Type I, Type II (SEDDS), and Type III formulations (SMEDDS). Oil phase for topical formulations. Oily vehicle and solubilizer for solutions (parenteral, auricular).	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions, Penetration enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafil® M 1944 CS Gattefossé	Solubilizer for poorly-soluble API and bioavailability enhancer Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion – LFCS type II (SEDDS) Combine with Labrasol®ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS) Co-emulsifier in topical formulations often associated with Tefose® 63 in antifungal cream	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafil® M 2125 CS Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion—LFCS Type II (SEDDS). Combine with Labrasol® ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS).	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafil® M1944 CS Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Injectables, Topical Penetration and Permeation enhancer	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Injectables, Topical Penetration and Permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrasol® Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrasol® Gattefossé	Solubilizer and O/W surfactant for microemulsion. Able to form light foams with pump device (no gas required).	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Topical penetration/permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrasol® ALF Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into microemulsion—LFCS Type III (SMEDDS). High purity guaranteed for stability and capsule compatibility.	Guaranteed for low aldehyde levels. Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Topical penetration/permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
LauroglycolTM 90 Gattefossé	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Lauroglycol™ FCC Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulation.	Water insoluble cosurfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions, Penetration enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Maisine CC Gattefossé	Solubilizer for lipophilic API and bioavailability enhancer. Oily vehicle for LFCS Type I (oily), Type II (SEDDS) and Type III (SMEDDS), associated with lymphatic absorption.	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Peceol™ Gattefossé	Solubilizer for lipophilic APIs and bioavailability enhancer. Oily vehicle containing long-chain fatty acids (C18:2) for LFCS Type I (oily), Type II (SEDDS), and Type III (SMEDDS), associated with lymphatic absorption. Oily vehicle for topical formulations.	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Plurol® Oleique CC 497 Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulations.	Water insoluble cosurfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions, Penetration enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Transcutol HP Gattefossé	Inquire	Solubilizer, Co-solvent, Component of SELF, emulsions and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Transcutol® HP Gattefossé	High purity solvent for all types of dosage forms, capsules, Injectables, inhalation products, Co-solvent in SMEDDS, solutions, suspensions, Topical Penetration and Permeation enhancer	High purity solvent for all types of dosage forms, capsules, Injectables, inhalation products, Co-solvent in SMEDDS, solutions, suspensions, Topical Penetration and Permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Nisso HPC – hydroxypropyl cellulose Nisso America Inc	Coating Systems, Viscosity Modifier, Solubilizer, Controlled Release, Binder, Emulsifier, Plasticizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
CRYSMEB Roquette Pharma	Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Glucono-Delta-Lactone Roquette Pharma	Solubilizer	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Maize Starch Roquette Pharma	Solubilizer, Disintegrant	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Potato Starch Roquette Pharma	Solubilizer, Disintegrant	Inquire	Get quote White Paper SDI Phase	Compare or Get quote for selected.