Increased Bioavailability Excipients

Excipients are generally pharmacologically inert, but can interact with drugs in the dosage form and the physiological factors at the site of absorption to affect the bioavailability of a drug product. The use of specific excipients with enhanced bioavailability properties can assist with getting the active ingredient into the bloodstream.

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Product / Company	Functionality	Application	Price
Captisol® Captisol®, A Ligand Technology	Solubilizer, Increased bioavailability, Stabilizer	Improves solubility, stability, bioavailability and dosing of APIs	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Capryol PGMC Gattefossé	Inquire	Solubilizer, Bioavailability enhancer, Water insoluble surfactant for SELF, Solubilizer for actives, W/O surfactant	Get quote White Paper SDI Phase	Compare or Get quote for selected.
CapryolTM 90 Gattefossé	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, Inhalation products, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, Inhalation products, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 44/14 Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 48/16 Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 50/13 Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into coarse emulsion—LFCS Type III (SMEDDS). Modulation of drug release. Lipid binder in melt processes.	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Matrix for modified release, Multiparticulates	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafac™ PG Gattefossé	Oily phase for topical formulations. Oily vehicle and solubilizer for solutions.	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafac™ lipophile WL 1349 Gattefossé	Oily vehicle in LFCS Type I, Type II (SEDDS), and Type III formulations (SMEDDS). Oil phase for topical formulations. Oily vehicle and solubilizer for solutions (parenteral, auricular).	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions, Penetration enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafil® M 1944 CS Gattefossé	Solubilizer for poorly-soluble API and bioavailability enhancer Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion – LFCS type II (SEDDS) Combine with Labrasol®ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS) Co-emulsifier in topical formulations often associated with Tefose® 63 in antifungal cream	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafil® M 2125 CS Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion—LFCS Type II (SEDDS). Combine with Labrasol® ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS).	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrafil® M1944 CS Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Injectables, Topical Penetration and Permeation enhancer	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Injectables, Topical Penetration and Permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrasol® Gattefossé	Solubilizer and O/W surfactant for microemulsion. Able to form light foams with pump device (no gas required).	Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Topical penetration/permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrasol® Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Solubilizer, Bioavailability enhancer, Surfactant in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Labrasol® ALF Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into microemulsion—LFCS Type III (SMEDDS). High purity guaranteed for stability and capsule compatibility.	Guaranteed for low aldehyde levels. Water dispersible surfactant, Solubilizer, Bioavailability enhancer, Component of SELF, Topical penetration/permeation enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
LauroglycolTM 90 Gattefossé	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Solubilizer, Bioavailability enhancer, Co-solvent in capsule filling, SMEDDS, Solutions, Suspensions, Topical Penetration and Permeation enhancer, Processing aid	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Lauroglycol™ FCC Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulation.	Water insoluble cosurfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions, Penetration enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Maisine CC Gattefossé	Solubilizer for lipophilic API and bioavailability enhancer. Oily vehicle for LFCS Type I (oily), Type II (SEDDS) and Type III (SMEDDS), associated with lymphatic absorption.	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Peceol™ Gattefossé	Solubilizer for lipophilic APIs and bioavailability enhancer. Oily vehicle containing long-chain fatty acids (C18:2) for LFCS Type I (oily), Type II (SEDDS), and Type III (SMEDDS), associated with lymphatic absorption. Oily vehicle for topical formulations.	Oily vehicle, Solubilizer, Bioavailability enhancer, Component of SELF	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Plurol® Oleique CC 497 Gattefossé	Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulations.	Water insoluble cosurfactant, Solubilizer, Bioavailability enhancer, Component of SELF and microemulsions, Penetration enhancer	Get quote White Paper SDI Phase	Compare or Get quote for selected.