Diluent Excipients

Diluent Excipients

Diluents act as fillers in pharmaceutical tablets to increase weight and improve content uniformity. Natural diluents include starches, hydrolyzed starches, and partially pregelatinized starches. Common diluents include anhydrous lactose, lactose monohydrate, and sugar alcohols such as sorbitol, xylitol and mannitol. Diluents provide better tablet properties such as improved cohesion or to promote flow. Mannitol is one of the costliest dilents, however, it is still often used due to the sensation it provides when it is used in chewable tablets. Diluents must be non-toxic, commercially available in acceptable grade, physiologically inert, and physically and chemmically stable by themselves as well as in combination with active pharmaceutical ingredients (APIs).

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Product / CompanyFunctionalityApplicationPrice 
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J.T. Baker PanExcea MC200
Avantor Performance Materials
DiluentInquire
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galenIQ™ 960
BENEO-Palatinit GmbH
DiluentInquire
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Lactochem®Microfine Micronised lactose
DFE Pharma
DiluentWet granulation / Extrusion spheronisation
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Lactochem® Extra Fine Powder
DFE Pharma
DiluentWet granulation / Extrusion spheronisation
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Pharmacel®101 Microcrystaline cellulose
DFE Pharma
Filler - Binder/ DiluentDry granulation / Wet granulation / Extrusion spheronisation.
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Pharmacel®102 Microcrystaline cellulose
DFE Pharma
Filler - Binder/ DiluentDirect compression / Dry blending
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Pharmacel®112 Microcrystaline cellulose
DFE Pharma
Filler - Binder/ DiluentDirect compression / Dry granulation / Dry blending
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Pharmatose® Milled lactose grades
DFE Pharma
DiluentWet granulation / Extrusion spheronisation
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Pharmatose® Sieved lactose grades
DFE Pharma
DiluentDry blending
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Prejel PA5 PH Fully pregelatinised potato starch
DFE Pharma
BinderWet granulation
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SuperStarch®200 Partly pregelatinised maize starch
DFE Pharma
Filler - Binder and Distegrant/ Binder and DisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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SuperTab®21AN Anhydrous lactose
DFE Pharma
Filler - Binder/ DiluentDirect compression / Dry granulation / Dry blending
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SuperTab®22AN Anhydrous lactose
DFE Pharma
Filler - Binder/ DiluentDirect compression / Dry granulation / Dry blending
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SuperTab®24AN Anhydrous lactose
DFE Pharma
Filler - Binder/ DiluentDirect compression / Dry blending
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SuperTab®30GR Granulated lactose
DFE Pharma
Filler - Binder/ DiluentDirect compression / Dry blending
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GranuLac 70
MEGGLE USA
DiluentInquire
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MicroceLac 100
MEGGLE USA
Diluent, BinderInquire
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RetaLac
MEGGLE USA
Diluent, Disintegrant|LubricantInquire
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StarLac
MEGGLE USA
Diluent, BinderInquire
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EMPROVE Lactose Monohydrate powder
MilliporeSigma
DiluentInquire
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EMPROVE exp Special Tabletting Grade Lactose Monohydrate
MilliporeSigma
DiluentInquire
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EMPROVE® exp D(-)-Mannitol powder
MilliporeSigma
DiluentInquire
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Extra Pure Sodium Hydrogen Carbonate
MilliporeSigma
DiluentInquire
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AceCel 101 (MCC 101)
Sigachi
Binder, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility, Wet GranulationInquire
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AceCel 102 (MCC 102)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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AceCel 103 (Low moisture MCC 101)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Dry Granulation, Filler, Moisture-Sensitive Active Ingredient, Natural OriginInquire
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AceCel 105 (MCC 105)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Tablet Compressibility, Wet GranulationInquire
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AceCel 112 (Low moisture MCC 102)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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AceCel 113 (Low moisture MCC 101)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Moisture-Sensitive Active Ingredient, Natural Origin, Tablet CompressibilityInquire
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AceCel 12 (MCC 12)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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AceCel 200 (MCC 200)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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AceCel 301 (High BD MCC 101)
Sigachi
Capsule Filling, Carrier, Diluent, Filler, Natural OriginInquire
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AceCel 302 (High BD MCC 102)
Sigachi
Capsule Filling, Binder, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Powder Blends, Natural Origin, Tablet CompressibilityInquire
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HiCel 12 (MCC 12)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel 14 (Low Moisture MCC 12)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel 25M (MCC 105)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Tablet Compressibility, Wet GranulationInquire
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HiCel 50M (MCC 101)
Sigachi
Binder, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility, Wet GranulationInquire
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HiCel 90M (MCC 102)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel HD50M (High BD MCC 101)
Sigachi
Capsule Filling, Carrier, Diluent, Filler, Natural OriginInquire
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HiCel HD90M (High BD MCC 102)
Sigachi
Capsule Filling, Binder, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Powder Blends, Natural Origin, Tablet CompressibilityInquire
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HiCel LM50 (Low moisture MCC 101)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Moisture-Sensitive Active Ingredient, Natural Origin, Tablet CompressibilityInquire
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HiCel SMCC 50M (SMCC 101)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel SMCC HD 90M (SMCC 102)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel SMCC LM 90M (SMCC 102)
Sigachi
Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel XLM 200 (Low moisture MCC 200)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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HiCel XLM 90 (Low moisture MCC 102)
Sigachi
Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet CompressibilityInquire
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