Disintegrant Excipients

Disintegrants are added to oral solid dosage forms to aid in their deaggregation. Disintegrants are formulated to cause a rapid break-up of solids dosage forms when they come into contact with moisture. Disintegration is typically viewed as the first step in the dissolution process. Examples of disintegrants include Crosslinked polymers, including crosslinked polyvinylpyrrolidone (crospovidone), crosslinked sodium carboxymethyl cellulose (croscarmellose sodium), and the modified starch sodium starch glycolate.

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Product / CompanyFunctionalityApplicationPrice 
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KICCOLATE Croscarmellose Sodium
Asahi Kasei
DisintegrantInquire
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PC-10 Pregelatinized Starch
Asahi Kasei
DisintegrantInquire
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J.T. Baker PanExcea MC200G
Avantor Performance Materials
Disintegrant, BinderInquire
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J.T. Baker PanExcea MHC300
Avantor Performance Materials
DisintegrantInquire
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J.T. Baker PanExcea MHC300G
Avantor Performance Materials
DisintegrantInquire
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Ludiflash
BASF North America
BinderReady-to-use ODT solution with superior mouthfeel
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Primellose® Croscarmellose sodium
DFE Pharma
SuperdisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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Primojel® Sodium starch glycolate
DFE Pharma
SuperdisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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Solani Amylum Native potato starch
DFE Pharma
DisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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SuperStarch®200 Partly pregelatinised maize starch
DFE Pharma
Filler - Binder and Distegrant/ Binder and DisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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EMCOSOY® - Soy Polysaccharides
JRS Pharma
DisintegrantCapsules, Chewables, Direct compression, Extrusion/spheronization, Roller compaction, Wet granulation
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EXPLOTAB® - Sodium Starch Glycolate
JRS Pharma
DisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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VIVASOL® - Croscarmellose Sodium
JRS Pharma
DisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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VIVASOL® GF - Crosscarmellose Sodium
JRS Pharma
DisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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VIVASTAR® P - Sodium Starch Glycolate
JRS Pharma
DisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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VIVASTAR® PSF - Sodium Starch Glycolate
JRS Pharma
DisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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RetaLac
MEGGLE USA
Diluent, Disintegrant|LubricantInquire
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Tablettose 100
MEGGLE USA
Sweetener, DisintegrantInquire
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Tablettose 70
MEGGLE USA
Sweetener, DisintegrantInquire
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Tablettose 80
MEGGLE USA
Sweetener, DisintegrantInquire
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EMPROVE Papain 30000 USP-U/mg Stabilized with Sodium Disulfate
MilliporeSigma
DisintegrantInquire
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EMPROVE Papain 6000 U/mg Stabilized with Sodium Disulfate
MilliporeSigma
DisintegrantInquire
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EMPROVE Parteck ODT Directly Compressible Disintegrant
MilliporeSigma
DisintegrantInquire
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EMPROVE® Parteck® Delta M Mannitol
MilliporeSigma
Binder, Disintegrant, Active Pharmaceutical IngredientInquire
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Extra white maize starch
Roquette Pharma
DisintegrantInquire
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Maize Starch
Roquette Pharma
Solubilizer, DisintegrantInquire
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PEARLITOL Flash mannitol-starch for orodispersable tablets
Roquette Pharma
Rapid Release Agent, DisintegrantInquire
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Potato Starch
Roquette Pharma
Solubilizer, DisintegrantInquire
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STARLAC lactose-starch
Roquette Pharma
DisintegrantInquire
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STARLAC lactose-starch compound
Roquette Pharma
DisintegrantInquire
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Wheat Starch TB
Roquette Pharma
DisintegrantInquire
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BARETab PH
Sigachi
Multifunctional, Binder, Glidant, Lubricant, Disintegrant, Natural Origin, Tablet CompressibilityInquire
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Hilose CCS (50µ)
Sigachi
Cellulose Filling, Disintegrant, Dissolution Accelerator, Rapid Release AgentInquire
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Stargel Type A
Sigachi
Cellulose Filling, Disintegrant, Dissolution Accelerator, Rapid Release AgentInquire
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Polyplasdone™ crospovidone
Ashland Inc.
SuperdisintegrantPeroxide sensitive APIs Orally disintegrating tablets (ODT) Tablets that require fast disintegration With poorly soluble APIs With poorly compressible APIs
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EXPLOTAB® CLV - Sodium Starch Glycolate
JRS Pharma
DisintegrantChewable Tablets, Ingestible Tablets, Dispersible Tablets, Effervescent Tablets, Soluble Tablets, Veterinary Applications, Stickpacks
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EXPLOTAB® Low pH - Sodium Starch Glycolate
JRS Pharma
DisintegrantChewable Tablets, Ingestible Tablets, Dispersible Tablets, Effervescent Tablets, Soluble Tablets, Veterinary Applications, Stickpacks
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EXPLOTAB® PCF - Sodium Starch Glycolate
JRS Pharma
DisintegrantChewable Tablets, Ingestible Tablets, Dispersible Tablets, Effervescent Tablets, Soluble Tablets, Veterinary Applications, Stickpacks
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PROSOLV® EASYtab Nutra CM - All-in-One, Ready-to-Use Excipient Composite:Binder, Glidant, Superdisintegrant, Lubricant Microcrystalline Cellulose, Colloidal Silicon Dioxide, Croscarmellose, Palm Kernel Oil saturated, DATEM
JRS Pharma
High functionality excipientDirect Compression, Wet Granulation
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PROSOLV® EASYtab Nutra GM - All-in-One, Ready-to-Use Excipient Composite: Binder, Glidant, Superdisintegrant, Lubricant Microcrystalline Cellulose, Colloidal Silicon Dioxide, Croscarmellose, Palm Kernel Oil saturated, DATEM
JRS Pharma
High functionality excipientDirect Compression, Film Coating, Wet Granulation
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PROSOLV® EASYtab SP - All-in-One Excipient Composite: Binder-filler, Glidant, Superdisintegrant, and Lubricant (Microcrystalline Cellulose, Colloidal Silicon Dioxide, Sodium Starch Glycolate, Sodium Stearyl Fumarate)
JRS Pharma
High functionality excipientDirect Compression, Wet Granulation
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PROSOLV® EASYtab SP LM - All-in-One Composite: Binder-filler, Glidant, Superdisintegrant, and Lubricant Microcrystalline Cellulose, Colloidal Silicon Dioxide, Sodium Starch Glycolate, Sodium Stearyl Fumarate
JRS Pharma
High functionality excipientDirect Compression, Film Coating, Wet Granulation
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VIVAPHARM® PVPP XL - Crospovidone
JRS Pharma
SuperdisintegrantDisintegration
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VIVAPHARM® PVPP XL-10
JRS Pharma
SuperdisintegrantDisintegration
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VIVASTAR® P 1000 SF - Sodium Starch Glycolate
JRS Pharma
SuperdisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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VIVASTAR® P 3500 - Sodium Starch Glycolate
JRS Pharma
SuperdisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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VIVASTAR® P 5000 - Sodium Starch Glycolate
JRS Pharma
SuperdisintegrantCapsules, Chewables, Direct compression, Extrustion/Spheronization, Roller compaction, Wet granulation
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