Disintegrant Excipients

Disintegrants are added to oral solid dosage forms to aid in their deaggregation. Disintegrants are formulated to cause a rapid break-up of solids dosage forms when they come into contact with moisture. Disintegration is typically viewed as the first step in the dissolution process.

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Product / CompanyFunctionalityApplicationPrice 
KICCOLATE Croscarmellose Sodium
Asahi Kasei
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DisintegrantInquire
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PC-10 Pregelatinized Starch
Asahi Kasei
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DisintegrantInquire
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Polyplasdone™ Ultra crospovidone
Ashland Inc.		Effervescent System, DisintegrantDirect Compression, Dry Granulation, Wet Granulation
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Polyplasdone™ Ultra-10 crospovidone
Ashland Inc.		Effervescent System, DisintegrantDirect Compression, Dry Granulation, Wet Granulation
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Polyplasdone™ XL crospovidone
Ashland Inc.		Effervescent System, DisintegrantDirect Compression, Dry Granulation, Wet Granulation
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Polyplasdone™ XL-10 crospovidone
Ashland Inc.		Effervescent System, DisintegrantDirect Compression, Dry Granulation, Wet Granulation
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J.T. Baker PanExcea MC200G
Avantor Performance Materials		Disintegrant, BinderInquire
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J.T. Baker PanExcea MHC300
Avantor Performance Materials		DisintegrantInquire
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J.T. Baker PanExcea MHC300G
Avantor Performance Materials		DisintegrantInquire
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Ludiflash
BASF North America		BinderReady-to-use ODT solution with superior mouthfeel
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Primellose® Croscarmellose sodium
DFE Pharma		SuperdisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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Primojel® Sodium starch glycolate
DFE Pharma		SuperdisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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Solani Amylum Native potato starch
DFE Pharma		DisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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SuperStarch®200 Partly pregelatinised maize starch
DFE Pharma		Filler - Binder and Distegrant/ Binder and DisintegrantDirect compression / Dry granulation / Wet granulation / Dry blending
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EMCOSOY® - Soy Polysaccharides
JRS Pharma		DisintegrantCapsules Chewables Direct compression Extrusion/spheronization Roller compaction Wet granulation
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EXPLOTAB® - Sodium Starch Glycolate
JRS Pharma		DisintegrantCapsules Chewables Direct compression Extrustion/Spheronization Roller compaction Wet granulation
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VIVASOL® - Croscarmellose Sodium
JRS Pharma		DisintegrantCapsules Chewables Direct compression Extrustion/Spheronization Roller compaction Wet granulation
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VIVASOL® GF - Crosscarmellose Sodium
JRS Pharma		DisintegrantCapsules Chewables Direct compression Extrusion/spheronization Roller compaction Wet granulation
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VIVASTAR® P - Sodium Starch Glycolate
JRS Pharma		DisintegrantCapsules Chewables Direct compression Extrusion/spheronization Roller compaction Wet granulation
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VIVASTAR® PSF - Sodium Starch Glycolate
JRS Pharma		DisintegrantCapsules Chewables Direct compression Extrustion/Spheronization Roller compaction Wet granulation
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RetaLac
MEGGLE USA		Diluent, Disintegrant|LubricantInquire
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Tablettose 100
MEGGLE USA		Sweetener, DisintegrantInquire
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Tablettose 70
MEGGLE USA		Sweetener, DisintegrantInquire
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Tablettose 80
MEGGLE USA		Sweetener, DisintegrantInquire
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EMPROVE Papain 30000 USP-U/mg Stabilized with Sodium Disulfate
MilliporeSigma		DisintegrantInquire
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EMPROVE Papain 6000 U/mg Stabilized with Sodium Disulfate
MilliporeSigma		DisintegrantInquire
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EMPROVE Parteck ODT Directly Compressible Disintegrant
MilliporeSigma		DisintegrantInquire
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EMPROVE® Parteck® Delta M Mannitol
MilliporeSigma		Binder, Disintegrant, Active Pharmaceutical IngredientInquire
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Extra white maize starch
Roquette Pharma		DisintegrantInquire
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Maize Starch
Roquette Pharma		Solubilizer, DisintegrantInquire
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PEARLITOL Flash mannitol-starch for orodispersable tablets
Roquette Pharma		Rapid Release Agent, DisintegrantInquire
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Potato Starch
Roquette Pharma		Solubilizer, DisintegrantInquire
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STARLAC lactose-starch
Roquette Pharma		DisintegrantInquire
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STARLAC lactose-starch compound
Roquette Pharma		DisintegrantInquire
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Wheat Starch TB
Roquette Pharma		DisintegrantInquire
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