Anytime a medication has a bitter or unpleasant taste, it will result in low patient compliance. Taste masking excipients are used when the bitter taste of an active pharmaceutical ingredient (API) might impede patience compliance. Oral administration of bitter or unpleasant tasting medications is often the biggest obstacle for patients that fall into the pediatrics and geriatrics groups. These excipients usually are categorized as natural, artificial, nutritive, non-nutritive, polyols and novel.