Dry Granulation Excipients

Dry granulation is a common option to produce solid oral dosage forms when process efficiency is vital.

Dry granulation allows dry handling of moisture sensitive active pharmaceutical ingredients (API). It is also a good option when an efficient, low-cost tableting process is required.

The most common approach for dry granulation is roll compaction. During this process a powder blend of all relevant ingredients is compressed between two rotating mills. The resulting flakes are then fractioned to the specific particle size need. These particles are then ready for final tablet compression.

Roll compaction provides the following advantages:

A trusted functionality
Ready-to-use solutions when time-to-market is critical
Predictable scale-up
Continuous processing

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Product / Company	Functionality	Application	Price
Compritol® 888 ATO Gattefossé	Tablet Lubricant, Lipid Matrix for Sustained Release, Coating for Protection and Taste Masking. Oral Solid Dosage forms in Direct Compression, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization, Supercritical Fluid Extraction, Viscosity modification, Wet Granulation, Solid Lipid Nanoparticles, Nano Lipid Carriers	Tablet Lubricant, Lipid Matrix for Sustained Release, Coating for Protection and Taste Masking. Oral Solid Dosage forms in Direct Compression, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization, Supercritical Fluid Extrac	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 44/14 Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Gelucire® 48/16 Gattefossé	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Solubilizer, Bioavailability enhancer, Surfactant, for Solid Dispersions and SMEDDS in Capsule filling, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization	Get quote White Paper SDI Phase	Compare or Get quote for selected.
Precirol® ATO 5 Gattefossé	Lipid Matrix for Sustained Release, Coating for Protection and Taste Masking. Oral Solid Dosage forms in Direct Compression, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization, Supercritical Fluid Extraction, Viscosity modification, Wet Granulation, Solid Lipid Nanoparticles, Nano Lipid Carriers	Lipid Matrix for Sustained Release, Coating for Protection and Taste Masking. Oral Solid Dosage forms in Direct Compression, Dry Granulation, Film Coating, Hot Melt Extrusion, Roller Compaction, Spheronization, Supercritical Fluid Extraction, Viscosity mo	Get quote White Paper SDI Phase	Compare or Get quote for selected.